Binding of RNA by the Nucleoproteins of Influenza Viruses A and B

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Binding of RNA by the Nucleoproteins of Influenza Viruses A and B

This paper describes a biochemical study for making complexes between the nucleoprotein of influenza viruses A and B (A/NP and B/NP) and small RNAs (polyUC RNAs from 5 to 24 nucleotides (nt)), starting from monomeric proteins. We used negative stain electron microscopy, size exclusion chromatography-multi-angle laser light scattering (SEC-MALLS) analysis, and fluorescence anisotropy measurement...

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ژورنال

عنوان ژورنال: Viruses

سال: 2016

ISSN: 1999-4915

DOI: 10.3390/v8090247